What are Relaxants

Centuries ago, the Indians smeared their arrowheads with plant sap, which caused paralysis of the enemy’s muscles. The Europeans became interested in this property and, over time, began to investigate its medical qualities as well – that is how the first muscle relaxants appeared. Now these substances, which cause temporary muscle relaxation, are widely used by doctors for operations as well as to relieve spasms and cramps. If you are looking for specialized medications such as Liofen 10 mg, or you need to buy relaxants, then use reputable stores.

Use of relaxants

Such drugs are most common in two medical fields – anesthesiology and neurology. In anesthesiology, they are used to relax the muscles during surgeries in conjunction with anesthesia. This way the patient will not make involuntary movements that could lead to injury. In neurology they are used for the following pathological conditions: 

  • Complex therapy of osteochondrosis with pronounced spasms; 
  • Pain syndrome caused by disc hernias and muscle contractures; 
  • pathologies of the spinal cord, causing the development of spasms; 
  • Lumbar sciatica; strokes. 

Classification of medications

These medications can affect the functions of the human body in different ways. Depending on how they work, they are divided into three main groups: 

  • Depolarizing. Causes short-term muscle spasm by depolarizing the membrane that transmits nerve impulses to the muscles. This leads to a disruption of neuromuscular transmission, which allows the skeletal muscles to relax. When the action of the drug is no longer necessary, and in case of an overdose, cholinesterase is administered. 
  • Nondepolarizing. They block the H-cholinoreceptors, so that the muscle stops contracting. The effect of such medications can be stopped with proserpine. They are most often used for surgeries, including complex ones – they can act for up to 4 hours. 
  • Mixed type of action. 

They can affect different parts of the nervous system. Therefore, they are also classified according to the mechanism of action: 

  • Central action. They affect the nerve endings located in the brain or spinal cord, so the impulse is silenced at the very beginning of its formation and does not start the way to the corresponding muscles. 
  • Peripheral action. Block the transmission of nerve impulses from the spinal cord to the muscles, so they simply do not receive the signal to contract. 

These drugs are also divided by duration of action: 

  • long-acting – more than half an hour; 
  • medium-acting – from 20 to 30 minutes; 
  • short-acting – up to 10 minutes. 

They can be represented by the following dosage forms: 

  • Tablets. They are used for long-term symptomatic treatment of diseases accompanied by spasms and convulsions. Treatment begins with small doses. 
  • Injections. Most often these drugs are administered intravenously with syringes or infusion systems to relieve severe spasms and cramps, and before surgery. They may also be given directly into the cerebrospinal fluid. 

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